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General Category => Ask the Experts => Topic started by: Mall on February 07, 2003, 07:34:15 AM

Title: EPO
Post by: Mall on February 07, 2003, 07:34:15 AM
Also known as Epogen, and the similar drug Aransep, were developed primarily to treat kidney disease-related anemia by stimulating the production of red blood cells. Uses were later expanded to include people with HIV & on chemotherapy. Both medications are patented by Amgen.

There are a number of documented cases of  human athletes who have used EPO to increase their endurance in cycling & track competitions. In contrast, EPO was originally and properly used to treat anemia in horses, though some vets advised against it because of its potential to harm, or with prolonged use, even kill the horse. During this time, one group of sheets players who also owned a fairly large contingent of horses did a study of all of their horses to determine if EPO caused improved performance. Three mos & $80k later, they decided it did not & discontinued its use.

The big change came when it was learned that performance in longer races could be improved if the dosages used were increased drastically. Some believe this knowledge resulted from a study which was funded by a well known & well heeled breeder/owner with help from a vet who is suspected of playing an important role in EPO\'s proliferation. The advantages in using EPO, particularly after it was banned, are the well known ones that until recently there was no test to detect if it had been used, and it could be administered \"out of competition.\" Apparently, there are trainers who know more about administering it(and other illegal meds) than vets, and do it themselves. There apparently are also vets willing to do just about anything a trainer tells them to do, which is rationalized in the usual ways.

The \"sweep\" of the barns & the cars of racetrack vets which was conducted prior to the start of the last Sar meet, and another sweep which was conducted during the meet, were part of an effort to try to stop, or at least reduce, EPO use. In conjunction with the sweeps, all NY racetrack vets were required to sign a written acknowledgment that they would not possess or use EPO.

Hence, my enforcement idea, which I understood to be putting a band aid on one small part of a very big problem, while everyone was waiting for the EPO tests, was that the TRPB approach Amgen, alone or in conjunction with the DEA or FDA, agencies they have a working relationship with, and obtain documentation for any of the approx 250 NY racetrack vets who ordered or received EPO or Arensep after 9/1/02. This was done, but unfortunately the response was one I probably should have anticipated, namely that both drugs are distributed through wholesalers, who sell to intermediaries & pharmacies. I am led to believe that there is some way of tracking individuals who are ordering or receiving large amts of a particular drug, even when it\'s not classified as a narcotic. If anyone knows how to obtain it, the TRPB remains interested in info along these lines despite the new tests.

The above was pieced together based on discussions with two clean trainers & an honest vet, as well as a conversation with JB\'s Wall Street biotech buddy, who you should talk to BB, assuming you are serious about writing(or maybe coauthoring) an article on the subject. He was instrumental in exposing milkshaking & has a \"big picture\" idea for attacking the overall problem, which I am convinced both makes some sense & might be timely, given early signs coming from the Racing Medication and Testing Consortium and the proposed TBred \"Tour.\" However, I\'m afraid based on what I know now that an article on EPO would be historical in nature. As I see it, the old adage that the cheaters are one step ahead of the regulatory authorities falls into the category of gross understatment. It\'s more like five.

Title: Re: EPO
Post by: Silver Charm on February 07, 2003, 08:14:35 AM

Mall,

    We need some sort of a Fan Panel or Fan Commission which I\'ll nominate you as Chairman, whoever you are. Racing officials and trainers-ie(HBPA)will never do anything that has any substance to it (no pun intended).

    Maybe when the fans step up and present a reasonable set of proposals will the industry feel like \"Hey we better do something\".

    If you go back to when Dancers Image was disqualified after winning the Ky Derby for using Bute, it seems as though the rules have gotten softer not tougher. Butes ok in Ky now, Lasix is ok in NY now, Clenbuterol is ok for training purposes now, where does it stop!!

    Some trainers need drugs in order to win and keep their livelihood, tracks need horses to have a product, state officials need tracks to keep the tax revenue up. So why should we trust these people to do the right thing.

    Maybe the fans should do it themselves!!
Title: Re: EPO
Post by: magicnight on February 07, 2003, 11:34:27 AM
Mall;

Thanks for - once again - another insightful post.

I am interested in writing something, but I don\'t know how deeply I\'d get into EPO specifically. I\'m thinking along the lines of something directed at a general audience, bringing in both the fix-six and epo-drugs. David and Dasilva are scheduled for sentencing in mid-March; Harn about a month later. I think these upcoming events could be used to interest an editor in placing a story where the drift would be \"Here\'s one scandal being put to bed, and here\'s another bubbling under the surface that could blow the barn doors open.\"

I\'m going to work on it this weekend. If you\'d like to talk privately, nicely could give you my email address. If you\'d like, ask him for the \"BB\" email address (home). I\'m writing this from my office email.

Bob
Title: Re: EPO
Post by: Mall on February 07, 2003, 01:59:30 PM
Thank you Bob, for the offer and the kind words. In your article, you might want to be cautious about taking the position that the last scandal has been \"put to bed.\" I thought it was as well, at least isofar as scan bets are concerned. That\'s also the overall impression left by all of the pronouncements and articles. Unfortunately, and as hard as it is to believe, I learned recently from someone who was inside the mutuel room of a major track on a \"fact-finding mission\" that as of late last week scan betting is alive and well at one of the biggest racetracks in the country. In other words, the configuration of pk6 bets is still not being transmitted until after the 5th race at one major operation, so it might make some sense to avoid that bet and the superfecta until it is established beyond any doubt that the original problem which led to the fix six has actually been solved.